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SBP0151 – Glucagon-like Peptide 2, human

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SBP0151 – Glucagon-like Peptide 2, human
MW: 3766.7
Primary cleavage product of proglucagon in intestinal L cells. Recent studies indicate that GLP-2 has trophic action on the jejenum, ileum and colon. It , or analogues, should be potential candidates for treating short bowel syndrome.
Orskov C. et al. (1986) Endocrinology 119, 1467; Buhl T. et al. (1988) J. Biol. Chem. 263, 8621; Orskov C. et al. (1989) FEBS Letters 247, 193; Drucker D.J. et al. (1996) Proc. Natl. Acad. Sci. USA 93, 7911; Tsai C.H. et al. (1997) Am. J. Physiol. 272, G662.