SBP0088 – Urocortin, rat

Description:

SBP0088 – Urocortin, rat
MW: 4707.8
H-Asp-Asp-Pro-Pro-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH₂
Urocortin is a 40 amino acid peptide originally discovered in rat brain. It is a member of the CRF familiy which also includes the frog peptide sauvagine and the fish peptide urotensin. Indeed, urocortin shows a closer sequence homology to urotensin (63%) than to CRF (45%). Urocortin binds more effectively to CRF Type 2 receptors than CRF itself and is probably the endogenous ligand.
Vaughan et al. (1995) Nature 378, 287
500µg
1mg