SBP0087 – Urocortin, human

Description:

SBP0087 – Urocortin, human
MW: 4696.8
H-Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH₂
Following the discovery of urocortin in rat brain, the human peptide was cloned. Human and rat urocortin show 95% sequence homology. Human urocortin has been shown to bind to CRF-1, CRF-2alpha and CRF-2beta receptors as well as CRF-BP. Urocortin is reported to be more effective at suppressing appetite than CRF, but less potent at producing anxiety-like effects.
Donaldson et al. (1996), Endocrinology 137, 2167; Spina et al. (1996) Science 273, 1561.
500µg
1mg