Hydrazide Gel

Description:

PLEASE CHECK ALL PRICES WITH OUR MAIN OFFICE BEFORE PURCHASE.  +44 (0)1562 825286

Hydrazide Gel is a high efficiency glycoprotein binding medium, which will bind oxidized sugar molecules in the glycosyl groups of Anti-bodies and does not bind to amino acids. This important function makes it specific to immunoglobulins where the gycosylated area is distinctly located away from the hper-variable binding region. By using Hydrazide gel to exploit these antibodies may be linked to a solid phase support via the oxidized glycosyl groups.Thus preserving the antibody integrity, which no other linking method can guarantee. The method employs the oxidation of sugar molecules with sodium meta-periodate which converts vicinal pairs of hydroxyl groups to aldehydes, (-CHO), it is these which bind hydrazide agarose.